Integrin V3 On Human Endothelial Cells Binds Von Willebrand Factor Strings Under Fluid Shear Stress
Jing Huang; Robyn Roth; John E Heuser; and J Evan Sadler,
Washington University,
Blood,
113(989),
(2008)
Link To Paper
Abstract:
Acutely secreted von Willebrand factor (VWF) multimers adhere to endothelial cells support platelet adhesion and may induce microvascular thrombosi Keywords:
ultra-large von Willebrand factor; self association; integrin Materials & Methods:
Confluent HUVECs on glass-bottomed dishes (MatTek Ashland MA) were incubated with
EGM-2 medium containing 100 μM histamine (Sigma St. Louis MO) for 30 min at 37°C. Microscopic Technique
Fluorescence Microscopy, Immunofluorescence Cell Type(s)
U937 | 
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