Technical Reference #187

187.

The C-Terminal Polylysine Region And Methylation Of K-Ras Are Critical For The Interaction Between K-Ras And Microtubules Chen; Z.; Otto; J.; Bergo; M.; Young; S.; Casey; P.;, Duke University, The Journal of Biological Chemistry, 275(187), (2000)
Link To Paper

Abstract:
After synthesis in the cytosol Ras proteins must be targeted to the inner leaflet of the plasma membrane for biological activity. This targeting requires a series of C-terminal posttranslational modifications initiated by the addition of an isoprenoid li

Microscopic Technique
Fluorescence Microscopy

Cell Type(s)
3T3