Technical Reference #183

183.

Calcium Is A Key Signaling Molecule In ß-Lapachone-Mediated Cell Death Tagliarino; C.; Pink; G.; Dubyak; G.; Nieminen; A.L.; Boothman; D.;, Case Western Reserve University, The Journal of Biological Chemistry, 276(183), (2001)
Link To Paper

Abstract:
β-Lapachone (β-Lap) triggers apoptosis in a number of human breast and prostate cancer cell lines through a unique apoptotic pathway that is dependent upon NQO1 a two-electron reductase. Downstream signaling pathway(s) that initiate apoptosis following t

Microscopic Technique
Confocal Microscopy

Cell Type(s)
MCF-7