Technical Reference #181

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
glass-bottomed 6-cm petri dishes (MatTek Corp.)

181.

Capacitative Calcium Entry Deficits And Elevated Luminal Calcium Content In Mutant Presenilin-1 Knockin Mice Leissring; M.; Akbari; Y.; Fanger; C.; Cahalan; M.; Mattson;, University of California Irivine, The Journal of Cell Biology, 149(181), (2000)
Link To Paper

Abstract:
Dysregulation of calcium signaling has been causally implicated in brain aging and Alzheimer's disease. Mutations in the presenilin genes (PS1 PS2) the leading cause of autosomal dominant familial Alzheimer's disease (FAD) cause highly specific alterat

Microscopic Technique
Fluorescence Microscopy, Calcium Imaging

Cell Type(s)
isolated fibroblasts