Technical Reference #158

158.

The Actin-Binding Protein Hip1R Associates With Clathrin During Early Stages Of Endocytosis And Promotes Clathrin Assembly In Vitro Engqvist-Goldstein; Å.; Warren; R.; Kessel; M.; Keen; J.; Heuser4; J.; Drubin ; D.;, University of California Berkeley, The Journal of Cell Biology, 154(158), (2001)
Link To Paper

Abstract:
Huntington-interacting protein 1 related (Hip1R) is a novel component of clathrin-coated pits and vesicles and is a mammalian homologue of Sla2p an actin-binding protein important for both actin organization and endocytosis in yeast. Here we demonstrate

Keywords:
endocytosis; clathrin; F-actin; coated pits; Huntington’s disease

Microscopic Technique
Video Microscopy, Time Lapse

Cell Type(s)
COS-7