Technical Reference #1578

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
Glassbottom microwell culture dishes (35 mm; MatTek dishes)

1578.

Role Of A Novel Ph-Kinase Domain Interface In Pkb/Akt Regulation: Structural Mechanism For Allosteric Inhibition Veronique Calleja; Michel Laguerre; Peter J. Parker; Banashe Larijani, London Research Institute, PLOS Biology, 7(1578), (2009)
Link To Paper

Abstract:
Protein kinase B (PKB/Akt) belongs to the AGC superfamily of related serine/threonine protein kinases. It is a keyregulator downstream of various growth factors and hormones and is involved in malignant transformation andchemo-resistance. Full-length

Materials & Methods:
Okadaic acid sodium salt and AKT inhibitor VIII were from Calbiochem (Merck KGaA). Human PDGF was from R&D Systems. Phospho-Akt Thr-30

Microscopic Technique
Fluorescence Microscopy, Two-Photon

Cell Type(s)
3T3