Technical Reference #1439

Glass Bottom Culture Dishes

This study used MatTek product(s):

Citation in paper containing MatTek reference:
glass bottom dishes (MatTek)

1439.

Caveolin-1 Alters Ca2+ Signal Duration Through Specific Interaction With The G Q Family Of G Proteins Parijat Sengupta; Finly Philip and Suzanne Scarlata, Stony Brook University, The Journal of Cell Science, 121(1439), (2008)
Link To Paper

Abstract:
Caveolae are membrane domains having caveolin-1 (Cav1) as their main structural component. Here we determined whether Cav1 affects Ca2+ signaling through the G q–phospholipase-CB (PLCB) pathway using Fischer rat thyroid cells that lack Cav1 (FRTcav–) and

Keywords:
G proteins; Ca2+ signaling; Caveolin-1; Phospholipase C

Materials & Methods:
For imaging FRET and FCS experiments transfected cells were grown in glass bottom dishes (MatTek).

Microscopic Technique
Fluorescence Microscopy, Fluorescence Resonance Energy Transfer (FRET)

Cell Type(s)
FRTcav–